Industrial biotechnology - Biocatalysis for APIs - Cleantech
For more than 15 years, Protéus - a subsidiary of PCAS - has been developing biocatalytic processes for the synthesis of complex substances offering numerous advantages over conventional chemistry.
Thanks to our technological platform, we design and produce high-performance enzymes and microbial strains for use in biocatalysis. This enables us to offer innovative industrial solutions for bio-procedures using these enzymes and strains, to produce active pharmaceutical ingredients, for example.
Our platform includes proprietary technologies for directed molecular evolution (L-ShufflingTM and EvoSightTM) capable of creating new enzymes and microorganisms with highly enhanced performance levels. Protéus has a collection of enzymes and microorganisms unique in the world (including a large proportion of extremophiles), as well as technology transfer and scale-up to marketing expertise and capabilities.
- Automated platform for high-throughput screening
- Analytical facilities
- KiloLab, pilot and industrial production for biocatalytic processes
- Collection of over 8,000 strains derived from biodiversity
- Facilities to study aerobic and anaerobic microbiology
- Enzyme screening
- Advice for the selection of synthesis methods by biotransformation
- Enzyme development
- Study of protein expression in different industrial host systems
- Enzyme performance optimization via study of its formulation
- Enzyme performance optimization via protein engineering
- Process development:
- Expertise and know-how in the development of industrial enzyme processes and bioprocesses
- Process optimization and potential technology transfer
- Integration of the multidisciplinary expertise required to design, develop and produce enzymes and biocatalytic processes.
- A collection of enzymes and microorganisms drawn from the broadest biodiversity.
- An enzyme library (about 150) used for rapid testing on compounds of interest in biocatalysis: broad spectrum of activity for mild conditions, and/or in less conventional reaction fields, in terms of temperature, pH, or in the presence of high salinity.
- A diversity of enzymatic activity classes, as shown in the diagram below:
Enzymatic activity classes, as shown in the diagram:
To find out more about Protéus' activities, please contact us and visit our website.
- Epoxides and/or chiral diol
- Halogenated and/or alcohol- derived chiral