PCAS Group develops and manufactures Expansorb®, a range of biocompatible and biodegradable polymers (particularly Poly (D, L- lactide acid) and Poly (D,L-lactide, co-glycolide acid).
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PLA/PLGA biopolymers are used as a controlled and sustained delivery system of drug substances with continuous effect from one week to several months. These polymers are usually used to overcome multiple injections, high toxicity and to achieve the desired therapeutic effect by protecting the molecules with short in-vivo half-lives.
The application includes the controlled parenteral administration of drugs such as Peptides, therapeutic proteins, hormones, antibiotics, etc.
The second field is a medical device such as sutures and surgical plates. We are also expanding PLA/PLGA application by including medical imaging and regenerative medicine.
PLA & PLGA Polymers
- Bioabsorbable (metabolites) and biocompatible polymers
- Safety proven in human
- Designed for sustained release of drugs
- Polymers used into formulation of marketed drugs
- Known materials for medical devices
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Manufacture in accordance with highest cGMP Standards ICH Guide Q7a
- Drug Master File available (for our standards)
- Possible IMPD filling and DMF for new Expansorb
- Dedicated Polymers workshop
- Manufacturing under cGMP
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PCAS know-how and Expertise
- PCAS is a PLGA/PLA supplier for more than 15 years
- Scale up : from kgs to several hundred kgs
- Organic chemistry and polymers scale at the same site
- strong analytical development back up to meet high specifications
- Knowledge to fine tune your own polymer: PLA, PLGA derivatives, block copolymers,…
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Expansorb Catalog & custom
- 21 different biopolymers are available
- From R&D use to commercial scale
- Quality: cGMP grade
- Custom synthesized polymers tailored to your needs
- Expansorb® Catalog - Ask for a quote
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Expansorb Kit box
- PCAS is now offering a PLA/PLGA screening kit allowing researchers to find the adequate polymer for each formulation
- Choose your 8 samples of any polymer from our catalog (10g each)
- Select your kit box
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